Methods The mutation of mitochondrial DNA from all 18 family members of a chinese pedigree with maternally inherited aminoglycoside antibiotic-induced deafness was detected by PCR and DNA sequencing.
方法应用PCR和DNA序列分析技术,对一个有明确氨基糖苷类抗生素应用史的母系遗传耳聋家系共18人(包括聋人和听力正常者)的线粒体DNA进行研究。
With the idea of prevention of deafness into community, it will bring us a new challenge for all community-based and family-based rehabilitation.
随着“防聋走进社区”工作的开展,聋儿社区家庭的康复工作即将面临一个新的挑战。
Furthermore, none of mutation in deafness-associated GJB2 gene was detected in this Chinese family.
同时,在该家系中未发现GJB2基因及其他线粒体基因突变。
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