Estradiol acetate

• abstract: Estradiol acetate (INN, USAN, BAN; brand names Femtrace, Femring, Menoring) is a synthetic ester, specifically the 3-O-acetyl ester, of the natural estrogen, estradiol. It is relatively recent to the market, having been first approved in a vaginal ring formulation as Menoring in the United Kingdom in 2001, followed by another vaginal ring formulation as Femring in the United States in 2003, and finally as an oral preparation as Femtrace in the United States in 2004.

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