Objective: the effects of zinc deficiency and excess on cell cycle and cell apoptosis were explored to elucidate the mechanism of zinc action on bone growth and development.

目的探讨锌缺乏和锌过量对培养长骨细胞周期和细胞凋亡的影响，为阐明锌对骨骼的生长发育影响的机制提供科学依据。

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There were many apoptotic cells in zinc deficiency group and necrotic cells in zinc excess group.

电镜观察，缺锌组可见大量的凋亡细胞，而高锌组则有大量的坏死细胞。

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