What is it then? Something's up, isn't it?

那么这是怎么回事？出问题了，是不是？

《柯林斯英汉双解大词典》

What is it then that makes planning of software projects so hard?

那么到底是什么使得软件项目的计划如此之难呢？

youdao

What is it then that keeps him in this room, except the certainty that it’s still the best thing to do, the feeling that the whole absurd simplicity of the world has sought refuge here.

那又是什么让他留在这个房间里呢，不就是心中的一种确信，认为这样更好？ 不就是一种感觉，认为这世界简单到 荒谬 的一面全都遁迹此间？

youdao

And by learning what it is about economic development or housing that actually helps to improve health, we can then design more programs and ultimately make better use of the knowledge that we have."

VOA: special.2009.07.20

If in the catalog imagination is awakened, this is what it can then do for Richard.

如这里出现了幻想，这是理查的缘故。

耶鲁公开课 - 1945年后的美国小说课程节选

Specifically, what is it that American companies that, both then and now, still don't understand about China that you think you do and they don't?

美国公司对于中国的互联网行业，始终不甚了解,能否谈谈一些你知道而别人不知道的原因？

斯坦福公开课 - 百度CEO李彦宏演讲：全球最大搜索引擎的发展课程节选

What is it, then, when a scientist formulates a hypothesis that growth patterns follow temperature, and tests the hypothesis against data only to find that growth patterns do not follow temperature at all for 30% of the data and only partially for the rest?

ECONOMIST: Against the prevailing wind

For every time that Greece manages to reach what is demanded of it then more is demanded.

FORBES: Is Greece Being Forced to Default?

His core specialty is understanding technology, what it is now and what it could be, and then driving its evolution and market delivery to maximize corporate value.

FORBES: Announcing A Video Live Chat With Trevor Sumner Of LocalVox