He is engaging in dealing with a very difficult problem.

他正忙于处理一个棘手的问题。

youdao

It is a very difficult problem to look for the best equalization point between these two.

在这两者之间寻找最佳平衡点是一个困难的问题。

youdao

The automatic identification of seal imprints is a very difficult problem of pattern recognition.

印鉴自动识别是模式识别中的一项非常困难的课题。

youdao

She began to explain to the students how to solve a very difficult problem.

VOA: special.2009.10.25

Well, I talked about the problem of using plasmids in gene therapy, that it's very difficult to get them into cells.

我们之前讨论过,基因治疗中运用质粒的问题,质粒本身极难进入细胞

耶鲁公开课 - 生物医学工程探索课程节选

In fact there's research-- for example, this was done with internists, doctors, who are giving a very difficult, very difficult question connected to a liver problem that an individual patient had.

实际上有这样一项研究-,在内科医生，医生中间进行，向他们提出一个，与肝脏问题有关的很困难的问题,那是一个病人的病症。

哈佛公开课 - 幸福课课程节选

It strikes me that trying to define where the front lines are might become a very difficult problem in wartime.

NPR: Women in Combat: Rules and Reality

But Mr Clegg said the government had come up with a "fair and progressive solution to a very difficult problem".

BBC: Nick Clegg under fire in Commons over tuition fee rise

And this is a very, very difficult problem -- there is no question -- and it has been a problem that previous Presidents have worked to resolve.

WHITEHOUSE: Press Briefing