In that account, Howard Pomeranz of the University of Minnesota Medical School also noted seven other cases that had previously been mentioned in the medical literature.

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"If you're male, you're going to have to go through the rectum, " said Dr. Sayeed Ikramuddin, director of gastrointestinal surgery at the University of Minnesota Medical School.

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"All drugs given to populations work in some members of the population and not others, " says Jay Cohn, a cardiologist at the University of Minnesota Medical School in Minneapolis.

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