I used to enjoy cartoon in my childhood. I am not very clear when I began to be fed up with cartoon that is remote and alienable from my real life.

童年的时候曾经喜欢卡通片，我也记不清楚什么时候开始特别反感卡通片了，觉得卡通离现实生活特别遥远和有隔阂感。

youdao

A more plausible explanation would seem to be that people are fed up with the administration.

一个更合理的解释似乎是人们对行政机关感到厌倦。

《柯林斯英汉双解大词典》

I was pretty fed up when everyone failed to see what we had achieved in Iraq, but an audience with the Pope, who said, "It is you who should be baptising me", soon cheered me up.

当所有人对我们在伊拉克的战果视而不见时，我真的感到了厌烦。 但在一次见到教皇时，他说：“瞧瞧你的样子，好像是来给我施洗礼的。”

youdao

So although the New Critics were fed up with philological criticism, I don't mean to be condescending toward it or to suggest that it didn't play a crucially important role in the evolution of literary studies.

所以，虽然新批判主义,对语言学批判主义不满，但是并不是要否认语言学批判主义,在文学研究发展过程中,起到的重要作用。

耶鲁公开课 - 文学理论导论课程节选

The elite and an increasing number of ordinary Russians seem to be getting fed up with Mr Putin and his crony capitalism.

ECONOMIST: Russia's presidency

And that seems to be the predominant response from those fed up with the onslaught of downtime-related coverage and commentary over the past two days.

FORBES: Facebook Downtime Means Real-Life Repercussions for Blogosphere

Saturday afternoons were billed as 'an alternative to sport' as audience research had shown that listeners were fed up with sport and would be attracted to this alternative.

BBC: Wiltshire - A history of the BBC in Wiltshire