The study demonstrated that L5178Y TK gene mutation assay ism ore sensitive than micronucleus and comet assay.
与微核试验和彗星试验比较证实，L 5 178y细胞TK基因试验检测基因突变更加灵敏。
Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).
目的建立用人类淋巴母细胞TK 6检测纺锤体毒物——长春花碱的TK基因突变试验方法，同时探讨长春花碱的遗传毒性分子机理。
TK6 cells can be used as an in vitro assay system to assess cytogenetic damage and gene mutation at tk locus of environmental chemicals.
TK 6细胞可用于评估环境化学物细胞水平遗传改变及TK基因突变。
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