其化学结构式与三苯氧胺(Tamoxifen TAM)相似,抗肿瘤作用机制亦与TAM相似,但其具有的诱导转化生长因子(β-TGF)的产生和调节致癌表达从而抑制癌细胞的作用是TAM所缺乏的...
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Objective To investigate the effects of tamoxifen (tam) on proliferation of SHG-44 glioma cells and explore its possible mechanism.
目的研究三苯氧胺(TAM)对人脑胶质瘤细胞SHG - 44增殖的影响并探究其可能机制。
The objective response to antiestrogen tamoxifen (TAM)in advanced breast cancer with respect to its estrogen receptor (ER) Status was studied in 55 patients.
在55例晚期乳癌病人中研究了抗雌激素他莫昔芬(TAM)治疗效果和乳癌雌激素受体(ER)状态的关系。
Objective To study whether tamoxifen(TAM) can induce growth arrest and apoptosis of ER-negative MA782 mouse breast cancer cell line and to explore the molecular mechanisms.
目的探讨三苯氧胺(TAM)治疗乳腺癌分子作用机制及其与细胞周期的关系。
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