Study Design. A retrospective clinical study.

研究设计：一个回顾性的临床研究。

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Two randomized controlled trials (RCTs), one before-and-after study and two retrospective reports on clinical efficacy and safety were retrieved, together with 18 pharmacokinetic studies.

检索到与临床功效和安全性相关的两个随机对照试验(rct)、一个前后对照研究、两个回顾性报告，以及18个药物动力学研究。

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In a prior retrospective study, her group demonstrated a poor correlation between clinical and ultrasound findings in ankle disease with juvenile idiopathic arthritis, she said.

她说，在先前的回顾性研究中，她的小组证明超声与临床检查在青少年特发性关节炎踝关节病变中相关性较差。

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For one, the groups noted the analysis is a retrospective study, not a prospective, randomized controlled clinical trial, which many regard as a gold standard for ferreting out safety concerns.

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