There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.
肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。
The FHIT protein deletion in HCC was higher than that in paratumor tissues and normal liver tissues (P<0.01).
正常肝组织中全部呈阳性表达，HCC组织中FHIT蛋白缺失率显著高于相应癌旁及正常肝组织（P<0.01）。
Objective: To investigate the expression characteristics of FHIT protEin in breast carcinomas and its relationship with clinicopathological parameters.
目的：探讨FHIT基因蛋白在乳腺癌中的表达特点及其与临床病理参数的关系。
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