The origin recognition complex (ORC) is a highly conserved heterohexameric protein complex that associates with DNA at or near initiation of DNA replication sites.
起始识别复合物(ORC)是一种高度保守的异源六聚化蛋白复合体,它与DNA复制起始位点处或其附近的DNA相关。
The pre-replication complex (Pre-RC) forms in late mitosis/early G1 phase beginning with the binding of CDT1 and cdc6 to the origin, which allows binding of the heterohexameric MCM2-7 complex.
前复制复合体(Pre-RC)在有丝分裂末期/G1早期随着CDT1和cdc6的结合而形成,允许异源六聚化的MCM2-7复合体的结合。
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