Notch信号与牙胚发育和牙齿损伤 - 牙易网——口腔医学,牙科行业门户 关键词】 Notch信号; 牙胚发育; 损伤修复 [gap=640]Key words] Notch signaling; tooth development; dental repair
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Notch signaling pathway 信号通路 ; notch信号途径 ; 利用高通量基因芯片 ; 路径
Notch signaling molecule Notch信号分子
notch signaling transduction notch信号传导
Notch signaling transduction pathway Notch信号转导通路
This made a prediction that Notch signaling should be active in stem cells and mostly inactive during commitment.
这样就有一个预测是,Notch信号在干细胞中应该是有活性的,而在定向的过程中是几乎没有活性的。
We set up in collaboration with him and this allowed us to show that Notch signaling was in fact highly enriched in stem cells, and was rapidly shut off as stem cells differentiated.
我们和他进行了合作,这就让我们表明了Notch信号事实上在干细胞中是很多见的,而一旦干细胞开始分化它就会中断了。
Further studies will examine the relationship among the Notch, Hedgehog and Wnt pathways in glioblastoma and look for other signaling processes that help tumors become resistant to therapy, he says.
更深入的研究将会阐释恶性胶质瘤中Notch Hedgehog和Wnt通路之间的关系,并寻找使肿瘤产生耐药性的其他信号传导途径,他说。
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