There may be some matters of life and death or highest principle, which might justify such a risk, but there aren't many things that fall in this category.

也许有一些关乎生死或最高原则的事情可以证明这种冒险是合情合理的，但属于这一类别的事情并不多。

youdao

Matters of life and death have been preoccupying me a lot recently.

最近，生与死的问题一直困扰着我。

youdao

Most especially must I tread with care in matters of life and death.

极为重要的是我的工作常常与病人生死有关。

youdao

For all comic novels that are any good must be about matters of life and death.

所有好的喜剧小说写的,必须包含生与死的问题。

耶鲁公开课 - 1945年后的美国小说课程节选

It holds in its memory all matters of life and death and love.

NPR: An Athlete of God

Matters of life and death and public health are emotional matters indeed.

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The Supreme Court usually gets the last word in these matters, regardless of whether one agrees with their decisions -- even matters of life and death, which many argue are the stakes in this health care debate.

CNN: STORY HIGHLIGHTS