Since 2006, American mobiloil group has been making a significant impact in Canada's emerging biofuels industry.

自2006年以来，美国美孚国际石油集团一直在加拿大的新兴生物燃料行业有着重大的影响力。

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"We're training the 21st Century workforce, and making a significant impact on local Michigan nonprofits," says Bud Gibson, an Eastern Michigan University professor of computer information systems.

“我们正在培训21世纪的劳动力，并对密歇根当地非盈利组织产生重大影响”，东密歇根大学计算机信息系统教授巴蒂·吉布森说。

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Of course, just like last time, truly rolling out these new technologies would ultimately have a significant impact on oil prices, potentially making it cheap again.

当然，就像上次那样，真铺开这些新技术，将会最终对油价产生重大影响，可能会再次让石油变得便宜。

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Meanwhile, monetary policy remains accomodative but has little chance of making a significant impact on housing, including the latest move by the Federal Reserve.

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For the past 18 months, I have been speaking publicly about desktop virtualization, and at every conference I keep stressing the inevitability of the smartphone making a significant impact on desktop virtualization.

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Along with a wide television viewership opportunity, March Madness presents advertisers with the possibility of making a significant digital impact.

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