My tutor, Professor Zhang Yu-zhen considers the pathogeny of POF is deficiency of kidney and spleen, liver-qi stagnation and blood stasis.

导师张玉珍教授认为本病的发生主要的病因病机为肾脾亏虚，肝郁血瘀。

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Weakness of the spleen and stomach and liver depression and Qi stagnation were more popular in young patients, kidney-Yang deficiency was more common in older patients;

脾胃虚弱、肝郁气滞证多出现在青年人中，肾阳虚衰证多出现在老年人中；

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