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Janus kinase

两面神激酶

JAK即Janus Kinase(两面神激酶),是…

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Janus激酶

新型类风湿关节炎治疗药物托法替尼 - 中国新药杂志关键词：类风湿关节炎；Janus激酶；托法替尼 [gap=542]Key words： rheumatoid arthritis; Janus kinase; tofacitinib

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激酶

作为两面神激酶(janus kinase,JAK)一51,AT途径中JAK激酶的底物,STAI,S在细胞因子(Cytokine,CK)的信号转导中起着...

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是酪氨酸激酶

STAT1结构及功能的研究进展 al transducer and activator of transcription,STAT)是酪氨酸激酶(Janus kinase,JAK)-STAT信号传递途径中的重要环节,通过这一途径细胞信号可以从细胞外传递到细胞内,使相关基因活化,实

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短语

Janus kinase 1 蛋白酪氨酸激酶 ; janus激酶

Janus protein tyrosine kinase 氨酸激酶 ; 蛋白酪氨酸激酶 ; 酪蛋白激酶

Janus activated kinase JAK家族酪氨酸激酶 ; Janus活化激酶

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医药科学

·2,447,543篇论文数据，部分数据来源于NoteExpress

abstract: Janus kinase (JAK) is a family of intracellular, nonreceptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they were just two of a large number of discoveries in a PCR-based screen of kinases,) but were ultimately published as "Janus kinase".

以上来源于: WordNet

Janus kinase drugs may also work well in rheumatoid arthritis a potentially even bigger market.

FORBES: The Next Big Rare Disease Drug?
The big sleeper is tasocitinib, a so-called janus kinase inhibitor, for rheumatoid arthritis and psoriasis.

FORBES: Pfizer's Big Pipeline Hope
Inycte and Novartis are competing with numerous other drug companies including AstraZeneca, Eli Lilly, and Sanofi-Aventis (which is acquiring privately held Targegen and its janus kinase drug).

FORBES: The Next Big Rare Disease Drug?

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