Conclusion: Inducing differentiation is the primary effect of HMBA on HL60 cells, and inducing apoptosis is not.
结论:HMBA对HL60细胞的作用主要是促进分化,诱导凋亡不是主要作用机制;
BACKGROUND: the methods of inducing the differentiation of bone marrow stromal cells into osteoblasts included the differentiation under chemicals effect, cytokine effect and transgenosis.
背景:现阶段诱导骨髓基质细胞分化成骨的方法大致分为在化学药物作用、细胞因子作用以及转基因作用下的分化等。
Conclusion TATS has a differentiation inducing effect on untreated and recurrent APL, with haematological CR and cytogenetic CR achieved.
结论TATS对初治及复发APL有一定的诱导分化作用,单药TATS治疗初治及复发apl患者可达到血液学和细胞遗传学缓解。
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