He did it in disregard of any advice.

他不顾一切劝告做了这件事。

youdao

They adopted the decision in disregard of our repeated warnings.

他们置我们的多次警告于不顾，采纳了该项决定。

youdao

Star singers, painters and calligraphers, authors… all go in for self-packaging overtly in disregard of public ridicule.

包装歌星、包装书画家、包装著作……包装早已是堂而皇之的事业，不怕社会讥讽了。

youdao

In the extreme case, where we disregard taxes and we have to disregard some other problems, we get the same answer.

在极限情况下,忽略税的因素,再忽略一些其他因素,就得出了同样的答案

耶鲁公开课 - 金融市场课程节选

Complete disregard of life is rampant in some terrible laboratories.

在一些实验室内，这种毫不重视生命的做法十分猖獗。

需要动物实验吗？ - SpeakingMax英语口语达人

Maybe someday the British--United Kingdom-- something will happen to it, it will fall apart or change, but that is so distant in the future that we can disregard that, so we'll take that as forever.

或许有人会说英国,大英帝国,总会有突发事件发生,政权会发生改变,但至少现阶段不会改变,我们可以忽视它,因此我们就认为它是永久存在的了

耶鲁公开课 - 金融市场课程节选

People will invariably vote for their ends in disregard for the community or any inkling of how society prospers.

FORBES: If On The Dole Why Do You Still Get To Go To The Poll?

Once, when he saw a new building that he thought the community had erected for itself, in disregard of the rule of poverty, he climbed up to the roof and began prying off the tiles and throwing them to the ground.

NEWYORKER: Rich Man, Poor Man

The World Conference on Human Rights expresses grave concern about continuing human rights violations in all parts of the world in disregard of standards as contained in international human rights instruments and international humanitarian law and about the lack of sufficient and effective remedies for the victims.

UNESCO: Vienna Declaration and Programme of Action