These findings suggest that daily activity in patients with severe heart failure may not simply be limited by the failing heart, but also by an impairment in the leg muscles themselves.

这些发现说明，严重心脏衰竭患者的日常活动不仅仅是简单地受到心脏衰竭的限制，还受到腿部肌肉自身损伤的限制。

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Hypertension is one major cardiovascular disease, which usually causes the impairment of target organs, especially heart.

高血压是最常见的心血管疾病之一，常导致心脏等靶器官功能损害。

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In the field of cardiac surgery, valve replacement is an effective approach to treat valve disorders, however, all of heart valves can be used clinically have different degrees of impairment.

在心脏外科领域中，人工心脏瓣膜置换术是治疗心脏瓣膜性病变的主要外科治疗手段，然而，临床上可以使用的人工心脏瓣膜存在不同程度的缺陷。

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But a renegade group of doctors use it for a far broader range of ills--everything from heart disease to memory impairment--despite scant evidence it works and potentially dangerous side effects.

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