How vexing!; How annoying!

多么烦人呀！

《新英汉大辞典》

Lectures, exhibits and hands-on experiments will explore how chemical research can help solve vexing global problems related to food, water, health, energy and transportation.

讲座，展览和亲身经历会打开一扇门，告诉你化学研究是如何解决全球性的棘手问题，比如说食品、水、健康、能源和运输。

youdao

How far they might go to stop this remains a vexing question.

但是他们能够多大程度上阻止这种态势仍就是一个未知的问题。

youdao

He was looking for an answer to a question that was vexing him: how could he break into China's tightly controlled entertainment business?

WSJ: Katzenberg Unveils China Film Project

He is on sabbatical now and spends most of his time writing and occasionally lecturing on a vexing subject: How should people who call themselves Christians conduct their lives in the secular world?

FORBES: Magazine Article

Automakers still haven't figured out one of the most vexing problems about fuel cells: how to store enough hydrogen onboard.

FORBES: Fueling Hope