Background: HLA haploidentical bone marrow is a potential source of doner for children for its availability.
背景：人类白细胞抗原(HLA)半相合造血干细胞移植由于供源广泛，在儿科具有广阔的应用前景。
Methods: In this pilot study, 58 patients, 33 with high-risk or advanced leukemia, were transplanted with cells from an HLA-haploidentical family donor with at least 1 of 6 loci mismatched.
方法：5 8例血液恶性肿瘤患者，33例为高危或难治复发白血病，接受了至少一个HLA位点不合的家庭供者造血干细胞移植。
Besides technological advances, choosing the most appropriate donor is also an important factor to overcome the HLA barriers in haploidentical HSCT.
为克服供受体h LA差异对半相合移植的不利影响，除改良移植技术之外，选择最为合适的供体也是决定手术成败的重要因素。
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