OBJECTIVE: To review the new methods and developments on hepatic targeting drugs during the past few years, and provide references of research and application for this kind of drugs.
目的:综述近几年研究的药物肝靶向性的新方法和新思路,为此类药物的开发和应用提供参考。
The results indicated that N-Lactosyl-Chitosan was a good ligand for ASGPR, and could be used as hepatic targeting carrier of antitumor drugs.
实验结果表明N-乳糖酰壳聚糖是ASGPR的特异性配基,对肝细胞具有“主动”靶向作用,可作为肝靶向载体。
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