has a large impact 威胁较大
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
Information technology has had a significant impact on the productivity of large enterprises.
信息科技已经对大型企业的生产力产生了重大的影响。
Building a kernel that is capable of protecting against itself is difficult, and usually has a large negative impact on performance.
构建一个具有防护来自自身攻击能力的内核很困难,并且通常这会对性能产生很大的负面影响。
Paper,for example,has little impact on the environment as it is being used, but requires large amounts of energy and resources for its production."
VOA: standard.2009.03.30
"The fact that unemployment has remained so high does suggest that the stimulus has not had as large an impact as the administration claims."
VOA: standard.2010.06.18
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