To analyze the relationship between multiple gene promoter methylation profile and the clinicopathological features of colorectal cancer.
探讨结直肠癌中多基因甲基化与蛋白表达之间的关系;
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
这种现象主要在印迹基因和X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
DNA methylation in the promoter regions is a powerful mechanism for the suppression of gene activity.
在启动子区域的DNA甲基化是抑制基因活性的一种重要机制。
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