A fundamental change in the organization of health services was required.

公共医疗在组织上需要有一个根本性的变革。

《牛津词典》

Satava says, "We are in the midst of a fundamental change in the field of medicine."

萨塔瓦说：“我们正处于医学领域的根本变革之中。”

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Industrialization not only produced a fundamental change in the way work was organized; it transformed the very nature of work.

工业化不仅从根本上改变了工作的组织方式，还改变了工作的本质。

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At the festive ceremony, the president acknowledged that this legislation will mark a fundamental change in U.S.domestic policy.

VOA: standard.2010.03.23

Notably, on Monday, the Treasury Department, under Secretary Henry Paulson, announced a proposal for fundamental change in our financial markets.

众所周知，在星期一，美国财务部部长，亨利·鲍尔森，宣布美国金融市场,将要改革的计划。

耶鲁公开课 - 金融市场课程节选

There have been fundamental changes through time that make the role of the central bank evolve and change through time.

试图保持系统的稳定,随着时间的发展，基本的改变发生,使得中央银行的角色演变。

耶鲁公开课 - 金融市场课程节选

Removing personal barriers may require a fundamental change in how CIOs view their capabilities and responsibilities.

FORBES: Time To Reinvent IT: CIOs Need New Skills, New Mindset

That might encourage an even more fundamental change in Germany: the revival of entrepreneurial spirit.

ECONOMIST: German restructuring

She's talking about a deal some see as a fundamental change in South Asia's geopolitical landscape.

NPR: Pakistan Uncertain About Relationship with U.S.