It exists in much tisues both in human and murine. MDM2 is correlated with P53, it is expressed highly in gastric cancer, carcinoma of bladder and fleshy tumor, but it is expressed lower in neighbour non-cancerous tissues.
MDM2基因在人的胃癌，膀胱癌，肉瘤组织中都有较高的表达，而在其相应的正常组织中的蛋白表达率较低，提示在肿瘤发生过程中，MDM2可能起着一定的作用。
参考来源 - TSG101在肺鳞癌、肺腺癌组织中的表达及其与MDM2的相关性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
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