First dose reaction 首剂效应
The immunogenicity of 12F6 in humans has been reduced though humanization. But the first-dose reaction associated with T cell activation by anti-CD3 Abs still exists.
人源化抗体解决了抗体鼠源性的问题，但CD3单抗激活T细胞引起首剂效应的问题仍然存在。
The results show that the degradation efficiency of DBS increases with the accretion of radiation dose of gamma rays and the degradation reaction of DBS seems following first-order kinetic.
结果表明，丁硫醚的去除率随辐射剂量的增加而上升，去除反应符合一级动力学；
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