MN9D多巴胺能细胞损伤模型的建立基-临床医学论文-中国论文联盟 关键词】 多巴胺能神经细胞;6-羟基多巴胺;MN9D细胞;帕金森病 [gap=898]Key words: dopaminergic cells; 6-OHDA; MN9D cells; Parkinson′s disease
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Objective To study the different expression of dopaminergic cells in different parts of rat gastrointestinal tract.
目的比较正常大鼠消化道不同部位多巴胺能细胞的分布性差异。
The hypothesis about maladjustment of transporters can explain preferably the mechanism of selective loss of the dopaminergic cells.
转运体失调学说能较好地解释多巴胺能神经元选择性缺失的机制。
CONCLUSION: MG132 can inhibit the proliferation of dopaminergic PC12 cells and lead to apoptosis. The disfunction of proteasome may do harm to the existence of dopaminergic cells.
结论:蛋白酶体抑制剂mg132能够抑制多巴胺能细胞PC 12的增殖并诱导细胞凋亡,蛋白酶体活性的丧失可能影响到多巴胺能细胞的生存。
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