However, some patients do not respond well to conventional ventilatory support, further complicating the treatment.

但常规性的通气支持对有些病人的作用不大，使治疗的复杂性进一步加大。

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Conclusion Regional nerve blockade may be a feasible, safe and effective treatment for congestive heart failure patients who do not respond well to the existing optimal medical therapy.

结论局部阻滞肾神经作为一种新的治疗慢性充血性心衰的方法是安全、有效并且是可行的，临床可用于治疗药物难以控制的心衰。

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Of the estimated 121m people who suffer from it, 15-30% have "refractory" cases like those treated by Dr Mayberg and Dr Lozano-that is, they do not respond to any treatment.

全球大约有一亿两全一百万人处于抑郁症痛苦中，15 - 30%患者像梅博格和罗扎诺医生的病人那样反顾发作难以抑制，对此前的任何治疗都麻木不仁。

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Plus, clinical experience with patients who describe themselves as Internet addicts has been that they do not respond to treatment in the same way that, for example, alcoholics and substance-abusers do.

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When malignant, islet cell cancers do not generally respond well to chemotherapy, and the treatment is mainly palliative.

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It would be best prescribed by GPs in the first instance and, if patients do not respond, that is the appropriate time to refer to a specialist for further investigation and treatment.

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