Memory loss, difficulty in performing familiar tasks, and problems with abstract thinking are all indicators of the beginning of the disease.
记忆力减退、做熟悉的任务出现困难、抽象思考出现问题，这些都是疾病开始的征兆。
"This creates a huge financial difficulty for us because you have to pay your bills, electricity and rent at the beginning of the month," he said in an interview.
“这给我们带来了极大的财政困难，要知道月初时你还得付账单，交房租和电费，”他在采访中说。
It could be difficult to get consistent income in the beginning because of the difficulty to find clients.
因为一开始很难找到客户，所以开始的时候很难得到稳定的收入。
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