This review focuses on how aberrant covalent histone modifications such as acetylation and methylation may contribute to the development of alimentary canal neoplasms.
主要探讨组蛋白共价修饰中乙酰化和甲基化在消化道肿瘤形成过程中的作用。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
The "histone code" is comprised of the covalent modifications of histone tails that function to regulate gene transcription.
“组蛋白密码”是由起调控基因转录功能的组蛋白末端的共价修饰所组成。
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