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constitutive androstane receptor 添加释义

网络释义英英释义

  烷受体

孕烷X受体(pregnane X receptor, PXR)和组成型雄甾烷受体(Constitutive androstane receptor, CAR)作为主要的核受体能够与RXRa形成异源二聚体,发挥调控CYP3A4和MDR1基因表达水平的作用。

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  组成性雄甾烷受体

...(thyroid hormone receptor，THR)、孕烷受体(pregnane X receptor, PXR) 和组成性雄甾烷受体(constitutive androstane receptor, CAR)等多种转录因子的调控。近期的体外研究数据表明，肝脏X受体(LXR)也对肝细胞中Thrsp转录起重要的调控作用。

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  组成型雄甾烷受体

组成型雄甾烷受体(Constitutive androstane receptor,CAR)和PXR一样也能与外源性配体结合从而调节CYP2B6、CYP3A4、CYP2C19、 【作者单位】：...

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  雄烷受体

组成性雄烷受体(constitutive androstane receptor, CAR)和孕烷X受体(pregnane X receptor,PXR)是NR1I核受体家族的两个重要成员。

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Constitutive androstane receptor

  • abstract: The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. CAR is a member of the nuclear receptor superfamily and along with PXR functions as a sensor of endobiotic and xenobiotic substances and in response upregulates the expression of proteins responsible for the metabolism and excretion of these substances.

以上来源于: WordNet

双语例句

  • Some of the mice lacked the gene needed to make the constitutive androstane receptor (CAR), a molecule involved in clearing away bile acid.

    一些小鼠缺乏制造雄烷受体(CAR)的基因(一种清除胆汁酸的分子)。此基因在胆汁酸水平过高时会被激活。

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