Prof. Laurent: They give importance to all classes, but they give more information for the prescription of a certain drug class for a certain indication.

新指南强调所有 类别的药物都是很重要的，除此之外，针对相应的适应症，指南会着重给出某些 类别药物的信息。

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Single lead VDD pacing in those with intact sinus node function (i.e. a young patient with congenital AV block) gets a class IIa indication.

FORBES: Overview of the New HRS/ACCF Pacemaker Guidelines

Sinus node dysfunction (SND) gets a clear endorsement for dual chamber (DDD) pacing with a class I indication, even in those without manifest AV conduction abnormalities.

FORBES: Overview of the New HRS/ACCF Pacemaker Guidelines

Rate responsive pacing is given a Class IIa indication in those with documented chronotropic incompetence.

FORBES: Overview of the New HRS/ACCF Pacemaker Guidelines