【摘要】： 进行基因定位最直按的方法是染色体原位杂交(Chromosomal in situ hybridization)。以前,这种技术都是用氚标记的探针完成,但使用氚有许多不便之处,诸如探针比活性低,常需多种~3H—dNTP共参入才能满足要求等。
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Detection of chromosomal abnormalities by fluorescence in situ hybridization (FISH) analysis has not been well-studied in FNA samples of pancreatic masses.
目前我们采用荧光原位杂交(FISH)分析法对胰腺肿块细针穿刺活检(FNA)样本行染色体异常检测还没有深入研究。
Objective To investigate the value of multiplex fluorescence in situ hybridization (M-FISH) in the detection of complex chromosomal abnormalities (CCAs) of chronic lymphocytic leukemia (CLL).
目的探讨多重荧光原位杂交(M - FISH)技术检测慢性淋巴细胞白血病(CLL)复杂核型异常(CCA)的价值。
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