Molinari's superb four-under 68 in testing conditions has left the Italian Ryder Cup star one shot clear of South Africa's George Coetzee, Scotland's Marc Warren, Mark Foster of England and Spaniard AlejandroCanizares.
Germany's Martin Kaymer shot 68 to finish third on eight under with England's Lee Westwood (71), Sweden's Henrik Stenson (67) and Spain's AlejandroCanizares (71) eight shots back and American Dustin Johnson (69) nine behind.