Xinzhi buccal adhesive tablets 辛芷口腔黏附片
Conclusion: the good effect can be obtained on the buccal adhesive tablets when using CP and HPC (or HPMC) as the adhesive materials.
结论:CP与HPC(或HPMC)作为粘附材料制备丁卡因口腔粘附片能获得良好效果。
CONCLUSION the adhesive property of the tablets and the release behavior of drug are relevant. Also, the formulation of buccal adhesive tablets is optimized by adjusting the composition.
结论口颊黏附片的生物黏附性与体外释药行为具有一定的相关性,通过调整处方可筛选出生物黏附性和体外释药均较理想的处方。
Results:The buccal adhesive tablets of tetracaine prepared by CP and HPC(or HPMC)with 12 produced effect within 1~2min. The adhesive time in oral cavity was more than 3h, and above 10h at night.
结果:用CP与HPC(或HPMC)以12的比率制备的丁卡因口腔粘附片在1~2分钟内起效,口腔内的粘附时间大于3小时,夜间使用可达10小时以上。
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