There are two main methods to obtain chiral aromatic alcohols from prochiral aromatic carbonyl compounds . One is asymmetric addition reaction, the other is asymmetric reduction reaction.
本文综述了手性芳香醇合成的意义和主要合成方法,合成手性芳香醇主要是从潜手性的羰基化合物入手,采用不对称还原和不对称加成两种方式进行。
参考来源 - 不对称催化还原底物的制备及手性配体中间体的合成·2,447,543篇论文数据,部分数据来源于NoteExpress
On the contrary, pretreating with allyl bromide could turn the stereoselectivity of this asymmetric reduction reaction from mainly producingS-CHBE to R-CHBE.
而烯丙基溴预处理可以使反应立体选择性从通常的生成S-型产物过量转变为R-型产物过量,优化处理条件后能使R-CHBE的e。
In this review, asymmetric reduction of prochiral ketones and its recent advances have been described according to the reaction types.
按反应类型分类,综述了酮的不对称还原方法及其近年来的新进展。
Asymmetric hydroboration is a kind of widely applied and valuable reaction, in which borane reduction of prochiral ketones reaction is an important method.
不对称催化硼氢化反应是应用广泛且具有工业价值的反应,其中的硼烷还原前手性酮反应有着举足轻重的作用。
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