Abstract:In the anti-cancer drugs, there is a category of Antimetabolites drugs containing pyrimidine-tract structure such as Funimiding and Azacytidine.
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Results Mesenchymal stem cells were spindle-shaped and active proliferation capacity in vitro, they can be differentiation into cardiac-like muscle cells after adding 5-azacytidine.
结果大鼠骨髓基质细胞贴壁呈集落生长,5 -氮胞苷诱导骨髓基质细胞转化为心肌样细胞。
Bone marrow stem cells of young rats can form immature myocardial-like cells after in vitro culture labeling of 5-bromodeoxyuridine and induction of 5-azacytidine.
幼鼠骨髓干细胞经体外培养、5 -溴脱氧尿核苷标记和5 -氮杂胞嘧啶核苷诱导能形成幼稚的心肌样细胞。
AIM: To study morphological and molecular biological feature of differentiation of umbilical cord blood stem cells in vitro after induced by 5-azacytidine into cardiomyocytes.
目的:观察脐血间充质干细胞经5-氮杂胞苷诱导在体外定向分化为心肌样细胞的形态学及分子生物学特征。
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