The catalytic center of an enzyme is composed of a set of amino acids whose three-dimensional arrangement forms the "active-site" that allows them to efficiently bind and modify the substrate.

酶的催化中心是由一组氨基酸组成，其三维结构形成活性位点，允许它高效地结合或修饰底物。

youdao

Basic single-chain polypeptide that inhibits numerous serine proteases by binding to the active site of the enzyme, forming tight complexes.

基本的单链多肽，通过与酶的活性位点紧密结合形成复合物，抑制大多数的丝氨酸蛋白酶。

youdao

Chemical modification studies showed that the sulfhydryl, guanido, amino, carboxyl and indolyl groups may participate in the active center of the enzyme.

化学修饰实验发现：巯基、胍基、氨基、羧基和吲哚基可能参与酶活性中心的组成。

youdao

Dr Wilson and his colleagues have discovered that the complex finds its way to the active site of a viral enzyme known as reverse transcriptase.

ECONOMIST: Nanotechnology in biology

Using this data, Adams in 1995 concocted an unusual boron molecule that snuggled into one of the enzyme's active sites and blocked its function.

FORBES: Magazine Article

Besides the evolutionary odds against such a drastic change happening, a big alteration in the shape of its active site might well render an enzyme and thus the virus ineffective.

ECONOMIST: Nanotechnology in biology