I am loyal to my family and I made a major decision.

我很顾家，于是做了个重大决定。

youdao

It was in that moment that I had made a major decision.

从那一刻起，我便做了一个重大决定。

youdao

Making a job change is a major decision, a long-term commitment that I take very seriously.

改变工作是一个重要决定，这是我非常认真对待的长期承诺。

youdao

The next major change in Winslow Homer's life was a decision to work in a new medium.

VOA: special.2010.07.25

That's again up to the board to decide or they can set up a committee on the board that would decide, but ultimately, that's a major decision to send out dividends.

这也是由董事会决定的,他们可以建立一个委员会来负责此事,但最终,发放股利是个重大的决定

耶鲁公开课 - 金融市场课程节选

The decision was a major one. It forced the huge company to separate into thirty-six different companies.

VOA: special.2010.04.25

Ruth finished with a takedown to clinch a major decision, giving the Nittany Lions a crucial extra team point.

WSJ: Cornell's Dake 1st to win 4 titles at 4 weights

Remedy: When we make a major decision such as accepting (or turning down) a job offer, we tend to exercise confirmation bias.

FORBES: How To Remedy Your Top Career Regrets In Time For 2013

"It's a major decision that's cost us the game, " Ferguson told MUTV.

BBC: Queiroz questions referee Wiley