鹅膏毒素学名amanitin,分子式C39H54N10O13S, 是从剧毒磨菇中分离出来的一种多肽物质,属于毒伞肽类毒素,是一种强烈毒素,其毒性要强于毒鼠强,它可在几天之内摧毁人们的肝和肾,人们会清醒的感受到来自于身体的极度疼痛,直至昏迷、死亡。
研究鹅膏毒素致肝损害的机理,对小白鼠腹腔注射鹅膏菌毒素,利用琼脂糖凝胶电泳法研究肝细胞凋亡。
To study the mechanism of hepatic damaging due to amatoxins. Researching the apoptosis in mouses hepatic cell with agarose electrophoresis.
研究了致命鹅膏中的毒素在安全剂量下抑制小鼠皮肤肿瘤的效果,并对此毒素的药用安全性进行初步评价。
Inhibition effect of the toxin in Amanita exitialis on mouse skin papillomas under safe dose and the drug safety was evaluated primarily.
结论:鹅膏蕈毒素可引起氧化损伤作用,白藜芦醇可减轻这种损害程度。
Objective: To explore the oxidative damage induced by phalloides and the protective effect of white pigweed mellow on the damage.
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