目的对饮水型高氟病区进行流行病学调查及实验室检测，研究地方性氟中毒患者骨代谢的生化敏感标志物。
Objective To Study sensitive mark of biochemistry of bone metabolize of The Endemic Fluorosis by epidemiology examine and lab check up in high fluorine area of drinking water.
骨生化标志物是有用的监测骨吸收或合成代谢疗法的效果，并可能有助于查明谁有骨折的高风险。
Biochemical bone markers are useful for monitoring the efficacy of antiresorptive or anabolic therapy and may aid in identifying patients who have a high risk of fracture.
近代通过测定骨转换生化标志物了解是否存在骨代谢的失衡。
Molecular markers of bone turnover are helpful tools to detect the dynamics of the metabolic imbalance.
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