化疗药通过干扰细胞的生物周期,杀死肿瘤细胞;但是靶向药物,尤其是常用的TKI(酪氨酸酶抑制剂),作用机理是控制肿瘤的生长,而不是直接杀死它。肾肿瘤是一类富含血管的肿瘤,它的生长和转移与血管密切相关。
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...Tyrosine kinase inhibitors; Targeted therapy [gap=627]关键词: 胆管癌; 表皮生长因子受体信号通路; k-ras; 西妥昔; 酪氨酸酶抑制剂; 靶向治疗 ...
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酪氨酸激酶抑制剂 tyrosine-kinase inhibitor ; TKI ; tyrosine kinase inhibitor ; EGFR-TKI
酪氨酸蛋白激酶抑制剂 Ruxolitinib ; tyrosine kinase inhibitor ; TKI
受体酪氨酸激酶抑制剂 receptor tyrosine kinase inhibitor
酪氨酸羟化酶抑制剂 tyrosine hydroxylase inhibitors
的酪氨酸激酶抑制剂 tyrosine kinase inhibitor
和酪氨酸激酶抑制剂 tyrosine kinase inhibitor
一种酪氨酸激酶抑制剂 TKI ; tyrosine kinase inhibitor
高效酪氨酸激酶抑制剂 Tyrosinekinasesi nhibitors ; TKI
对酪氨酸激酶抑制剂 tyrosine kinase inhibitors
目的探讨白蒺藜中酪氨酸酶抑制剂的微波提取工艺。
Research on Extraction Technology of Resveratrol from Roots of Peanut;
介绍了最近几年来关于酪氨酸蛋白磷酸酯酶1B作用的机制以及通过各种途径发现的结构新颖的小分子抑制剂的构效关系研究进展。
The advances made in the new compounds identified as Protein Tyrosine Phosphatases 1B (PTP1B) inhibitors recently and their structure-activity relationship were reviewed in this paper.
本发明的化合物还可用作以磷酸酪氨酸结合区如SH 2结构域为特征的其它酶的抑制剂。
The compounds of the present invention may also be employed as inhibitors of other enzymes characterized with a phosphotyrosine binding region such as the SH2 domain.
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