载药量（loadingefficiency）是指单位重量或单位体积微球所负载的药量，其中能释放的药量为有效载药量。除药物与基质发生不可逆结合外，载药量可看成是微球的含药量。通常微球的载药量比脂质体高，白蛋白微球中水溶性药物的含量可达冷冻干燥载体重量的35%，水不溶性药物使用微型混悬或乳化方法也可达到高的载药量。
...双胍 载药量 [gap=1004]rosslinking method; sodium alginate; polyvinyl alcohol; metrormin hydrochloride; drug-loading rate ...
基于170个网页-相关网页
2载药磁性聚N-聚异丙基丙烯酰胺微球的制备 5.2.3配置DOX标准溶液作标准曲线 5.2.4微球的载药量(Drug loading efficiency，DLE)和药物的包封率(Drug entrapment efficiency，DEE)的测定 5.2.5...
基于8个网页-相关网页
Therefore, the pH value of calcium chloride solution was chosen at 4. Under this pH value, the embedding ratio was 60%, and drug-loading rate was 11%.
因此,本实验选定氯化钙溶液的pH值为4,在此pH值下BSA的包埋率可以达到60%,凝胶微球的载药量可以达到11%。
参考来源 - pH敏感型海藻酸钙多孔凝胶微球的制备及应用The average diameter was(44.99±12.59)μm,the drug loading capacity was (10.25±0.08)%,the encapsulation efficiency was(30.61±1.46)%.
平均粒径为(44.99±12.59)μm,载药量为(10.25±0.08)%,包封率为(30.61±1.46)%。
参考来源 - 人参皂苷Rg3鼻腔给药微球制剂的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
研究发现改进的乳化交联法能获得载药量较高的明胶微球。
The drug load in microspheres was enhanced by a modified emulsion crosslink method.
结论：我们制备出了稳定、载药量较大、包封率较高脂质体。
Conclusion: Our prepared liposome shows larger loading capacity and better envelopment and stability.
结果表明，所得微球粒径适合，分布均匀，性质稳定，载药量和包封率均比较适宜。
The results showed that the particle size and distribution was suitable, quality was stable, drug-loaded and entrapment rate were fine.
应用推荐