...;载药率;体外释放 [gap=16540]Key words: premix membrane emulsification; microspheres; uniformity; loading efficiency; drug release in vitro ...
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根据测试结果 计算出GA-ALG 载药纳米粒中DOX 的含量, 按公式 (2) 和(3) 计算载药率(Drug Loading, DL) 和包封率 (Entrapment Efficiency, EE): DOX-loaded NPs ...
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不同的处理过程对样品的载药率也有一定的影响。
Samples of different processing on drug-loading rate has a certain influence.
该制备方法简单易行,载药率高,成本低,可实现自动化和规模化生产。
The preparation method has the advantages of simplicity, easy operation, high ratio of drug loading and low cost, and can realize automated and large-scale production.
结果被动载药法得到的包封率仅有13.3%,主动载药法的包封率最高可达84 . 6 %。
RESULTS The entrapment efficiency with passive loading was only 13.3%; while up to 84.6% with active loading method.
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