我们承担的国家自然科学基金项目中发现血清素转运体（SERT）是PAH重要病理机制之一，该发现结合国外研究进展提示PAH与抑郁症之间在SERT/SERT基因方面可能存在内在联系。
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血清素与情绪调节有关，而血清素转运体在其中的作用至关重要。
Serotonin is involved in mood regulation. Serotonin transporters are crucial to this job.
作者指出，应用低效血清素转运体抑制剂、与任何类型卒中的发病风险增高均相关。
Still, they point out, the use of low-potency inhibitors of the serotonin transporter is associated with an excess risk for any stroke type.
与其它类型抗抑郁药物相比，抗抑郁药物物联合高效血清素转运体抑制剂与卒中风险增高相关。
Use of antidepressants with high inhibition of the serotonin transporter was associated with a greater risk for stroke than use of other types of antidepressants.
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