...rix metalloproteinases, MMPs)起到重要作用,它通过破坏基质的降解平衡而促进肿瘤细胞突破基底膜和细胞外基质(Extracell matrix, ECM)构成的组织学屏障,向周围组织侵袭和远处组织转移.因此,MMPs近年已成为肿瘤侵袭和转移研究的热点.
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破基底膜和细胞外基质 Extracell matrix
在胃癌的侵袭核转移进程中,基底膜和细胞外基质的降解是一个最重要的特征。
Degradation of basement membrane and extracellular matrix structures are important features of the metastatic process of invasion and metastasis of gastric cancer.
目的观察缓激肽(BK)对高糖浓度下肾小球系膜细胞增殖和细胞外基质分泌的影响。
Objective To observe the effect of bradykinin(BK) on kidney mesangial cell multiplication and extracellular matrix secretion under high glucose environment.
这种增生膜的形成主要包括细胞的增生和细胞外基质的沉积。
The process contains the proliferation of cells and the accumulation of extracellular matrix components.
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