维生素B1（硫胺素）缺乏病又称脚气病，是常见的营养素缺乏病之一。若以神经系统表现为主称干性脚气病，以心力衰竭表现为主则称湿性脚气病。前者表现为上升性对称性周围神经炎，感觉和运动障碍，肌力下降，部分病例发生足垂症及趾垂症，行走时呈跨阈步态等。后者表现为软弱、疲劳、心悸、气急等。
在十九世纪末期，日本海军中的水兵就颇受脚气病的困扰。
During the late 1800s the Japanese navy was having a problem with beriberi among its sailors.
我患脚气病已有几年了，一到夏季需换上凉鞋才行。
I suffer from beriberi to already had a few years, need to change sandal to just go to the summer.
没有它我们会变得虚弱，不会生长，还可能会得脚气病。
Without it, we would be weak and would not grow. We also might develop beriberi.
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