1.2 脂联素基因结构及单核苷酸多态性(SNPs) 人类脂联素基因(ADIPOQ)是单拷贝基因，位于染色体3q27，全长约17kb，包括大小为18～4277bp的3个外显子和0.8、12bp的2个内含子。
基于144个网页-相关网页
...生部医药卫生期刊奖 - Powered by SupeSite 关键词] 脂联素基因；启动子；儿童；肥胖 [gap=1092]Key words] Adiponectin gene; Promoter; Children;Obesity ...
基于40个网页-相关网页
脂联素基因第2外显子 adiponectin gene exon
ObjectiveTo investigate the relationship between adiponectin gene polymorphism and obstructive sleep apnea hypopnea syndrome (OSAHS).
目的 探讨脂联素基因单核苷酸多态性（SNP）与阻塞性睡眠呼吸暂停低通气综合征（OSAHS）之间的关系。
参考来源 - 脂联素基因单核苷酸多态性与阻塞性睡眠呼吸暂停低通气综合征关系的研究Different genotypes in pig adiponectin gene and the association with meat quality traits were analyzed. The analysis indicated that the muscle tenderness and cooking percentage were significant difference between genotype AA and Aa(P＜0.05).
4.脂联素基因序列变异位点与肉质的关系分析表明:AA基因型和Aa基因型的嫩度值、熟肉率差异显著(P＜0.05)。
参考来源 - 猪脂联素基因遗传多态性及其与肉质性状的相关性研究Cloning and expression of Acrp30 gene in E. coli were also studied in Qinchuan cattle and this work was a basis for further research on its functions.
此外,对秦川牛脂联素基因进行了体外克隆、表达研究,为进一步的功能研究奠定了基础。
参考来源 - 黄牛脂联素基因遗传特性及在大肠杆菌中的表达研究Cloning and expression of Acrp30 gene in E. coli were also studied in Qinchuan cattle and this work was a basis for further research on its functions.
此外,对秦川牛脂联素基因进行了体外克隆、表达研究,为进一步的功能研究奠定了基础。
参考来源 - 黄牛脂联素基因遗传特性及在大肠杆菌中的表达研究·2,447,543篇论文数据，部分数据来源于NoteExpress
目的：观察非诺贝特对糖尿病大鼠血脂联素和脂联素基因的表达及内皮细胞功能的干预作用。
Objective: To investigate the effect of fenofibrate on the expression of adiponectin gene, the level of the plasma adiponectin and endothelial function in diabetic rats.
脂联素基因在猪肌肉组织中以高度甲基化状态为主，这一结果与该基因在肌肉组织中表达量相吻合。
In muscle tissues, the promoter hypermethylation status of adiponectin gene was detected, which was consistent with the expression of this gene.
结论：在3t3 - L1脂肪前体细胞分化过程中脂联素基因表达逐渐上调，可能有利于脂肪细胞的分化成熟。
Conclusions: Adiponectin gene mRNA expression is up-regulated during 3t3-l1 preadipocyte differentiation. It may contribute to the adipocyte differentiation and obesity.
应用推荐